Drug Information

Drug General Information
Drug ID
D06MMU
Former ID
DIB002689
Drug Name
LM-CD45
Synonyms
Anti-CD45, Baxter; Anti-CD45, Cantab
Drug Type
Antibody
Indication Transplant rejection [ICD9: 279.5, 996; ICD10:D89.8, T86] Phase 1 [524041]
Company
Cantab Biopharmaceuticals Ltd
CAS Number
CAS 339315-39-8
Target and Pathway
Target(s) Leukocyte common antigen Target Info [545346]
KEGG Pathway Cell adhesion molecules (CAMs)
T cell receptor signaling pathway
Fc gamma R-mediated phagocytosis
Primary immunodeficiency
NetPath Pathway TCR Signaling Pathway
IL2 Signaling Pathway
PANTHER Pathway B cell activation
JAK/STAT signaling pathway
T cell activation
Pathway Interaction Database BCR signaling pathway
TCR signaling in na&#xef
TCR signaling in na&#xef
CXCR4-mediated signaling events
Reactome Phosphorylation of CD3 and TCR zeta chains
Other semaphorin interactions
WikiPathways Interferon type I signaling pathways
EPO Receptor Signaling
B Cell Receptor Signaling Pathway
TCR signaling
Semaphorin interactions
References
Ref 524041ClinicalTrials.gov (NCT01678443) Monoclonal Antibody Therapy Before Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoid Malignancies. U.S. National Institutes of Health.
Ref 545346Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002932)

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.