Drug General Information
Drug ID	D06PLG
Drug Name	SB-203347
Synonyms	169527-42-8; SB-203347
Indication	Unspecified		Investigative	[1560098]
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Phospholipase A2	Target Info	Modulator
BioCyc Pathway	Phospholipases
KEGG Pathway	Glycerophospholipid metabolism
	Ether lipid metabolism
	Arachidonic acid metabolism
	Linoleic acid metabolism
	alpha-Linolenic acid metabolism
	Metabolic pathways
	Ras signaling pathway
	Vascular smooth muscle contraction
	Pancreatic secretion
	Fat digestion and absorption
Pathway Interaction Database	Fc-epsilon receptor I signaling in mast cells
Reactome	Acyl chain remodelling of PC
	Acyl chain remodelling of PE
	Acyl chain remodelling of PI
WikiPathways	Glycerophospholipid biosynthesis
References
Ref 1560098	SB 203347, an inhibitor of 14 kDa phospholipase A2, alters human neutrophil arachidonic acid release and metabolism and prolongs survival in murine endotoxin shock.

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