Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06QKD
|
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| Former ID |
DNC012797
|
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| Drug Name |
4-(4-Isopropyl-morpholin-2-yl)-benzene-1,2-diol
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C13H19NO3
|
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| Canonical SMILES |
CC(C)N1CCOC(C1)C2=CC(=C(C=C2)O)O
|
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| InChI |
1S/C13H19NO3/c1-9(2)14-5-6-17-13(8-14)10-3-4-11(15)12(16)7-10/h3-4,7,9,13,15-16H,5-6,8H2,1-2H3
|
||||
| InChIKey |
SUYJAACXNVNFGP-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Alpha-1A adrenergic receptor | Target Info | Inhibitor | [1] | |
| Alpha-1D adrenergic receptor | Target Info | Inhibitor | [1] | ||
| Alpha-1B adrenergic receptor | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Calcium signaling pathway | ||||
| cGMP-PKG signaling pathway | |||||
| Neuroactive ligand-receptor interaction | |||||
| AMPK signaling pathway | |||||
| Adrenergic signaling in cardiomyocytes | |||||
| Vascular smooth muscle contraction | |||||
| Salivary secretionhsa04020:Calcium signaling pathway | |||||
| Salivary secretion | |||||
| NetPath Pathway | IL2 Signaling PathwayNetPath_14:IL2 Signaling Pathway | ||||
| PANTHER Pathway | Alpha adrenergic receptor signaling pathwayP00002:Alpha adrenergic receptor signaling pathway | ||||
| Pathway Interaction Database | LPA receptor mediated events | ||||
| Reactome | Adrenoceptors | ||||
| G alpha (q) signalling events | |||||
| G alpha (12/13) signalling eventsR-HSA-390696:Adrenoceptors | |||||
| G alpha (12/13) signalling events | |||||
| WikiPathways | Monoamine GPCRs | ||||
| Calcium Regulation in the Cardiac Cell | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Endothelin Pathways | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| AMPK SignalingWP58:Monoamine GPCRs | |||||
| GPCRs, OtherWP58:Monoamine GPCRs | |||||
| Vitamin D Receptor Pathway | |||||
| AMPK Signaling | |||||
| References | |||||
| REF 1 | J Med Chem. 1992 Mar 20;35(6):1009-18.Conformational effects on the activity of drugs. 13. A revision of previously proposed models for the activation of alpha- and beta-adrenergic receptors. | ||||
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