Drug Information
Drug General Information | |||||
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Drug ID |
D06RKS
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Former ID |
DNC007971
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Drug Name |
1-(phenylsulfonyl)butan-2-one
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
Download2D MOL |
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Formula |
C10H12O3S
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Canonical SMILES |
CCC(=O)CS(=O)(=O)C1=CC=CC=C1
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InChI |
1S/C10H12O3S/c1-2-9(11)8-14(12,13)10-6-4-3-5-7-10/h3-7H,2,8H2,1H3
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InChIKey |
SMYSSDAIMUTBFY-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Corticosteroid 11-beta-dehydrogenase, isozyme 1 | Target Info | Inhibitor | [1] | |
KEGG Pathway | Steroid hormone biosynthesis | ||||
Metabolism of xenobiotics by cytochrome P450 | |||||
Metabolic pathways | |||||
Chemical carcinogenesis | |||||
NetPath Pathway | IL1 Signaling Pathway | ||||
FSH Signaling Pathway | |||||
PathWhiz Pathway | Steroidogenesis | ||||
Reactome | Glucocorticoid biosynthesis | ||||
WikiPathways | Prostaglandin Synthesis and Regulation | ||||
Metabolism of steroid hormones and vitamin D | |||||
Glucocorticoid & Mineralcorticoid Metabolism | |||||
References | |||||
REF 1 | Bioorg Med Chem. 2007 Jul 1;15(13):4396-405. Epub 2007 Apr 25.beta-Keto sulfones as inhibitors of 11beta-hydroxysteroid dehydrogenase type I and the mechanism of action. | ||||
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