Drug General Information
Drug ID	D06TEO
Former ID	DNC001483
Drug Name	UCL-1390
Drug Type	Small molecular drug
Indication	Eating disorder; Epilepsy; Pain [ICD9: 307.5, 338,780; ICD10:F50, R52, G89]		Terminated	[545875]
Therapeutic Class	Analgesics
Company	University College London
Structure		Download 2D MOL 3D MOL
Formula	C13H13N3O
Canonical SMILES	C1=CC(=CC=C1C#N)OCCCC2=CN=CN2
InChI	1S/C13H13N3O/c14-8-11-3-5-13(6-4-11)17-7-1-2-12-9-15-10-16-12/h3-6,9-10H,1-2,7H2,(H,15,16)
InChIKey	XQNBJFUWFIHAMW-UHFFFAOYSA-N
PubChem Compound ID	6421295
PubChem Substance ID	14773729, 43015452, 50460755, 85216391, 103333299, 103949990, 114519468, 129726526, 134340660, 139406641, 226949363, 249945933
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Antagonist	[536225]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 545875	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005172)
Ref 536225	Emerging drugs for eating disorder treatment. Expert Opin Emerg Drugs. 2006 May;11(2):315-36.

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