Drug Information

Drug General Information
Drug ID
D06TOD
Former ID
DNC000054
Drug Name
2R,4R-APDC
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538868]
Structure
Download
2D MOL

3D MOL
Formula
C6H10N2O4
InChI
InChI=1S/C6H10N2O4/c7-6(5(11)12)1-3(4(9)10)8-2-6/h3,8H,1-2,7H2,(H,9,10)(H,11,12)/t3-,6-/m1/s1
InChIKey
XZFMJVJDSYRWDQ-AWFVSMACSA-N
CAS Number
CAS 177945-46-9
PubChem Compound ID
5310984
PubChem Substance ID
7978587, 11056185, 15120503, 24276926, 26744280, 26752104, 39340717, 57359309, 75240015, 90343729, 91744841, 99223623, 103216567, 103949275, 114154977, 117518359, 118315296, 126594410, 127305654, 127305655, 127305656, 127305657, 127305658, 129762234, 131301572, 131400559, 134339562, 134339599, 135635420, 135649704, 137264922, 141428213, 143439230, 151993633, 152055475, 162449345, 164830906, 176224839, 180666389, 204433876, 223594614, 226522464, 241182231, 251875150
Target and Pathway
Target(s) Metabotropic glutamate receptor 2 Target Info Agonist [535209]
KEGG Pathway Neuroactive ligand-receptor interaction
Glutamatergic synapse
Cocaine addiction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Ionotropic glutamate receptor pathway
Metabotropic glutamate receptor group II pathway
Reactome G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
GPCR ligand binding
GPCR downstream signaling
References
Ref 538868(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1392).
Ref 535209Attenuation of seizures induced by homocysteic acid in immature rats by metabotropic glutamate group II and group III receptor agonists. Brain Res. 2001 Jul 27;908(2):120-9.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.