Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06UFH
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| Former ID |
DIB007578
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| Drug Name |
CZ-112
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| Indication | Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] | Terminated | [1] | ||
| Company |
Stehlin Foundation For Cancer Research
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| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
n12c(c3c(C2)cc2c([N+](=O)[O-])cccc2n3)cc2c(c1=O)COC(=O)<br />[C@@]2(OC(=O)CC)CC
|
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| CAS Number |
CAS 194414-80-7
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| Target and Pathway | |||||
| Target(s) | Toposisomerase-1 | Target Info | Inhibitor | [2] | |
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | DNA replication | ||||
| Pathway Interaction Database | Caspase Cascade in Apoptosis | ||||
| WikiPathways | Integrated Pancreatic Cancer Pathway | ||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011353) | ||||
| REF 2 | Pharmacology of camptothecin esters. Ann N Y Acad Sci. 2000;922:216-23. | ||||
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