Drug General Information
Drug ID
D06UOU
Former ID
DNCL002168
Drug Name
MGA271
Indication Refractory metastatic solid tumors [ICD9: 140-199, 210-229; ICD10:C00-C75, C7A, C7B, D10-D36, D3A] Phase 1 [524393]
Company
MacroGenics
Target and Pathway
Target(s) B7-H3 Target Info Modulator [544431]
KEGG Pathway Cell adhesion molecules (CAMs)
References
Ref 524393ClinicalTrials.gov (NCT01918930) Tissue Procurement Substudy for Participants in Study CP-MGA271-01. U.S. National Institutes of Health.
Ref 544431T Cell Coinhibition and Immunotherapy in Human Breast Cancer. Discov Med. 2012 October; 14(77): 229-236.

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