Drug Information

Drug General Information
Drug ID
D06VFF
Former ID
DIB006423
Drug Name
EGFR antisense DNA
Synonyms
Antisense therapy, UPCI; EGFR antisense DNA, University of Pittsburgh
Drug Type
Antisense drug
Indication Head and neck cancer [ICD9: 140-149, 140-229; ICD10:C07-C14, C32-C33] Phase 1/2 [522667]
Company
University of Pittsburgh
Target and Pathway
Target(s) mRNA of EGFR Target Info [544315]
References
Ref 522667ClinicalTrials.gov (NCT00903461) Safety and Efficacy of Radiation/Cetuximab Plus EGFR Antisense DNA for Head and Neck Squamous Cell Carcinoma. U.S. National Institutes of Health.
Ref 544315Antitumor Effects of EGFR Antisense Guanidine-Based Peptide Nucleic Acids in Cancer Models. ACS Chem Biol. 2013 February 15; 8(2): 345-352.

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