Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07AXM
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| Former ID |
DIB018646
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| Drug Name |
5-fluorotryptamine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C10H11FN2
|
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| InChI |
InChI=1S/C10H11FN2/c11-8-1-2-10-9(5-8)7(3-4-12)6-13-10/h1-2,5-6,13H,3-4,12H2
|
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| InChIKey |
ZKIORVIXEWIOGB-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID |
5564434, 7735714, 10255559, 11221143, 15147279, 41877473, 46238839, 47440683, 47811154, 57350523, 57565612, 57983926, 77830661, 85209828, 88542503, 92240011, 92722377, 99216130, 103100551, 103179297, 104860800, 113454595, 117509425, 117664556, 118055462, 123058997, 123110404, 124575378, 125325324, 125353490, 126580222, 126614834, 126618325, 126649600, 126662649, 127352012, 129915247, 131382028, 134348499, 135121714, 135649833, 135722527, 136376874, 136908893, 140114969, 143393605, 143493180, 152243162, 160812643, 162081812
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| Target and Pathway | |||||
| Target(s) | 5-hydroxytryptamine 1E receptor | Target Info | Agonist | [2] | |
| KEGG Pathway | cAMP signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Serotonergic synapse | |||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| 5HT1 type receptor mediated signaling pathway | |||||
| Reactome | Serotonin receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | Serotonin HTR1 Group and FOS Pathway | ||||
| Monoamine GPCRs | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 146). | ||||
| REF 2 | Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor. Eur J Pharmacol. 2004 Jan 26;484(2-3):127-39. | ||||
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