Drug General Information
Drug ID
D07BUH
Former ID
DIB009849
Drug Name
F-627
Synonyms
Recombinant human G-CSF dimer (neutropenia), Generon (Shanghai) Corporation Ltd
Indication Neutropenia [ICD9: 288; ICD10:D70] Phase 2 [525287]
Company
Generon
Target and Pathway
Target(s) Granulocyte colony-stimulating factor Target Info Modulator [550803]
KEGG Pathway Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
Hematopoietic cell lineage
Malaria
NetPath Pathway IL1 Signaling Pathway
TNFalpha Signaling Pathway
TCR Signaling Pathway
WikiPathways Cytokines and Inflammatory Response
Hematopoietic Stem Cell Differentiation
References
Ref 525287ClinicalTrials.gov (NCT02521441) A Phase II, Dose-finding Study of F-627 in Patients With Breast Cancer Receiving Myelotoxic Chemotherapy.
Ref 550803Clinical pipeline report, company report or official report of Generon (Shanghai) Corporation Ltd.

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