Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07DLA
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| Former ID |
DIB003500
|
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| Drug Name |
ISF-402
|
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| Synonyms |
Urinary tetrapeptide (diabetes), Monash University/International Diabetes Institute/Pallane; Urinary tetrapeptide (diabetes), Monash University/International Diabetes Institute/Dia-B Tech Ltd
|
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| Indication | Type 2 diabetes [ICD9: 250; ICD10:E11] | Phase 1 | [551040] | ||
| Company |
Dia-B Tech
|
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CC(=O<br />)O)[C@H](O)C)Cc1c[nH]cn1)C(C)C
|
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| Target and Pathway | |||||
| Target(s) | Insulin receptor | Target Info | Modulator | [530158] | |
| KEGG Pathway | Ras signaling pathway | ||||
| Rap1 signaling pathway | |||||
| cGMP-PKG signaling pathway | |||||
| HIF-1 signaling pathway | |||||
| FoxO signaling pathway | |||||
| PI3K-Akt signaling pathway | |||||
| AMPK signaling pathway | |||||
| Adherens junction | |||||
| Insulin signaling pathway | |||||
| Ovarian steroidogenesis | |||||
| Type II diabetes mellitus | |||||
| Non-alcoholic fatty liver disease (NAFLD) | |||||
| Aldosterone-regulated sodium reabsorption | |||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | Insulin Pathway | ||||
| Signaling events mediated by PTP1B | |||||
| Signaling events mediated by TCPTP | |||||
| Insulin-mediated glucose transport | |||||
| PathWhiz Pathway | Insulin Signalling | ||||
| Leucine Stimulation on Insulin Signaling | |||||
| References | |||||
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