Drug Information

Drug General Information
Drug ID
D07EPV
Former ID
DNCL002927
Drug Name
Teneligliptin
Drug Type
Small molecular drug
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Phase 1 [525204]
Company
Mitsubishi Pharma America
Structure
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2D MOL

3D MOL
Formula
C22H30N6OS
Canonical SMILES
CC1=NN(C(=C1)N2CCN(CC2)C3CC(NC3)C(=O)N4CCSC4)C5=CC=CC=C<br />5
InChI
1S/C22H30N6OS/c1-17-13-21(28(24-17)18-5-3-2-4-6-18)26-9-7-25(8-10-26)19-14-20(23-15-19)22(29)27-11-12-30-16-27/h2-6,13,19-20,23H,7-12,14-16H2,1H3/t19-,20-/m0/s1
InChIKey
WGRQANOPCQRCME-PMACEKPBSA-N
PubChem Compound ID
11949652
PubChem Substance ID
17390993, 24477456, 35020542, 80852136, 96025300, 126671556, 135262329, 137179501, 137460776, 152136343, 152258607, 160647441, 163319882, 163340589, 185970860, 198988098, 223680878, 224304487, 226524787, 242679293, 251971018, 252216392, 252439082, 252481245
Target and Pathway
Target(s) Dipeptidyl peptidase IV Target Info Modulator [543447]
KEGG Pathway Protein digestion and absorption
NetPath Pathway IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
References
Ref 525204ClinicalTrials.gov (NCT02449330) Teneligliptin on the Progressive Left Ventricular Diastolic Dysfunction With Type 2 Diabetes Mellitus Study.
Ref 543447(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1612).

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