Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07GIB
|
||||
| Former ID |
DCL000470
|
||||
| Drug Name |
AZD5672
|
||||
| Drug Type |
Small molecular drug
|
||||
| Company |
AstraZeneca
|
||||
| Structure |
|
Download2D MOL |
|||
| Formula |
C31H43F2N3O5S2
|
||||
| InChI |
InChI=1S/C31H43F2N3O5S2/c1-4-36(31(37)19-23-5-7-29(8-6-23)42(2,38)39)28-11-14-34(15-12-28)16-13-30(25-20-26(32)22-27(33)21-25)24-9-17-35(18-10-24)43(3,40)41/h5-8,20-22,24,28,30H,4,9-19H2,1-3H3/t30-/m1/s1
|
||||
| InChIKey |
QOSMEMHKXNNIGG-SSEXGKCCSA-N
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | C-C chemokinereceptor type 5 | Target Info | Antagonist | [550288] | |
| Pathway Interaction Database | IL12-mediated signaling events | ||||
| References | |||||
| Ref 531058 | Preclinical and clinical investigation of a CCR5 antagonist, AZD5672, in patients with rheumatoid arthritis receiving methotrexate. Arthritis Rheum. 2010 Nov;62(11):3154-60. | ||||
| Ref 542666 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7686). | ||||
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