Drug General Information
Drug ID	D07GTX
Former ID	DNC012708
Drug Name	(8-Hydroxy-2-oxo-2H-quinolin-1-yl)-acetic acid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533420]
Structure		Download 2D MOL 3D MOL
Formula	C11H9NO4
Canonical SMILES	C1=CC2=C(C(=C1)O)N(C(=O)C=C2)CC(=O)O
InChI	1S/C11H9NO4/c13-8-3-1-2-7-4-5-9(14)12(11(7)8)6-10(15)16/h1-5,13H,6H2,(H,15,16)
InChIKey	YRQSYBRKGTYSAL-UHFFFAOYSA-N
PubChem Compound ID	13683079
Target and Pathway
Target(s)	Aldose reductase	Target Info	Inhibitor	[533420]
BioCyc Pathway	Methylglyoxal degradation III
	Acetone degradation I (to methylglyoxal)
KEGG Pathway	Pentose and glucuronate interconversions
	Fructose and mannose metabolism
	Galactose metabolism
	Glycerolipid metabolism
	Metabolic pathways
NetPath Pathway	IL1 Signaling Pathway
	TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway	Fructose and Mannose Degradation
	Pyruvate Metabolism
	Pterine Biosynthesis
	Glycerolipid Metabolism
	Galactose Metabolism
WikiPathways	Metapathway biotransformation
	Polyol Pathway
	Metabolism of steroid hormones and vitamin D
References
Ref 533420	J Med Chem. 1986 Oct;29(10):2024-8.Synthesis and aldose reductase inhibitory activity of substituted 2-oxoquinoline-1-acetic acid derivatives.
Ref 533420	J Med Chem. 1986 Oct;29(10):2024-8.Synthesis and aldose reductase inhibitory activity of substituted 2-oxoquinoline-1-acetic acid derivatives.

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