Drug Information
Drug General Information | |||||
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Drug ID |
D07HHR
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Former ID |
DNC011371
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Drug Name |
CEPHALOCHROMIN
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
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Download2D MOL |
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Formula |
C28H22O10
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Canonical SMILES |
CC1CC(=O)C2=C(O1)C=C3C(=C2O)C(=CC(=C3C4=C(C=C(C5=C(C6=C<br />(C=C54)OC(CC6=O)C)O)O)O)O)O
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InChI |
1S/C28H22O10/c1-9-3-13(29)25-19(37-9)5-11-21(15(31)7-17(33)23(11)27(25)35)22-12-6-20-26(14(30)4-10(2)38-20)28(36)24(12)18(34)8-16(22)32/h5-10,31-36H,3-4H2,1-2H3
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InChIKey |
JGQBYBXYRUCBQY-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Induced myeloid leukemia cell differentiation protein Mcl-1 | Target Info | Inhibitor | [1] | |
KEGG Pathway | PI3K-Akt signaling pathway | ||||
MicroRNAs in cancer | |||||
NetPath Pathway | TCR Signaling Pathway | ||||
PANTHER Pathway | Apoptosis signaling pathway | ||||
CCKR signaling map ST | |||||
Pathway Interaction Database | E2F transcription factor network | ||||
Direct p53 effectors | |||||
IL6-mediated signaling events | |||||
HIF-1-alpha transcription factor network | |||||
WikiPathways | Apoptosis | ||||
miR-targeted genes in muscle cell - TarBase | |||||
miR-targeted genes in lymphocytes - TarBase | |||||
miR-targeted genes in leukocytes - TarBase | |||||
Apoptosis Modulation and Signaling | |||||
References | |||||
REF 1 | Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). | ||||
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