Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07HTX
|
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| Former ID |
DIB016248
|
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| Drug Name |
GL-331
|
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| Drug Type |
Small molecular drug
|
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| Indication | Colorectal cancer [ICD9: 153, 154; ICD10:C18-C21] | Discontinued in Phase 2 | [1] | ||
| Company |
University of North Carolina
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C27H24N2O9
|
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| Canonical SMILES |
[C@H]12[C@@H]([C@@H](c3c([C@H]1Nc1ccc([N+](=O)[O-])cc1)<br />cc1c(c3)OCO1)c1cc(c(c(c1)OC)O)OC)C(=O)OC2
|
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| CAS Number |
CAS 127882-73-9
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | DNA topoisomerase II | Target Info | Modulator | [2] | |
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002538) | ||||
| REF 2 | GL331, a topoisomerase II inhibitor, induces radiosensitization of human glioma cells. Anticancer Res. 2006 May-Jun;26(3A):2149-56. | ||||
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