Drug Information

Drug General Information
Drug ID
D07HZG
Former ID
DNC009418
Drug Name
PF-00734200
Drug Type
Small molecular drug
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Phase 2 [522028], [542437]
Structure
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2D MOL

3D MOL
Formula
C17H24F2N6O
InChI
InChI=1S/C17H24F2N6O/c18-17(19)2-5-25(12-17)15(26)14-10-13(11-22-14)23-6-8-24(9-7-23)16-20-3-1-4-21-16/h1,3-4,13-14,22H,2,5-12H2/t13-,14-/m0/s1
InChIKey
QWEWGXUTRTXFRF-KBPBESRZSA-N
PubChem Compound ID
11516136
PubChem Substance ID
16618118, 23644574, 74889044, 81054281, 99444853, 103595991, 104103769, 124490365, 134346623, 135262598, 137229907, 139937218, 160969423, 162723401, 178103985, 198938880, 223683648, 226555395, 247067401, 252216054
Target and Pathway
Target(s) Dipeptidyl peptidase IV Target Info Modulator
KEGG Pathway Protein digestion and absorption
NetPath Pathway IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
References
Ref 522028ClinicalTrials.gov (NCT00473525) 12 Week Study Of PF-00734200 For The Treatment Of Type 2 Diabetes Mellitus In Subjects Treated With Metformin. U.S. National Institutes of Health.
Ref 542437(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7413).

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