Drug General Information
Drug ID
D07JOS
Former ID
DIB013411
Drug Name
NS-004
Drug Type
Small molecular drug
Indication Hypertension [ICD9: 401; ICD10:I10-I16] Terminated [467608], [534399]
Company
NeuroSearch A/S
Structure
Download
2D MOL

3D MOL

Formula
C14H8ClF3N2O2
InChI
InChI=1S/C14H8ClF3N2O2/c15-8-2-4-12(21)11(6-8)20-10-3-1-7(14(16,17)18)5-9(10)19-13(20)22/h1-6,21H,(H,19,22)
InChIKey
WYLYBVMNGZOYOH-UHFFFAOYSA-N
CAS Number
CAS 141797-92-4
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Potassium channel Target Info Opener [534399]
References
Ref 467608(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4271).
Ref 534399Effects of K+ channel inhibitors and antagonists on NS-004 evoked relaxations in guinea-pig isolated trachea. Fundam Clin Pharmacol. 1997;11(1):78-82.
Ref 534399Effects of K+ channel inhibitors and antagonists on NS-004 evoked relaxations in guinea-pig isolated trachea. Fundam Clin Pharmacol. 1997;11(1):78-82.

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