Drug General Information
Drug ID
D07LNY
Former ID
DIB020762
Drug Name
prostaglandin A2
Synonyms
medullin; PGA2
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541431]
Structure
Download
2D MOL
Formula
C20H30O4
InChI
InChI=1S/C20H30O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h4,7,12-18,21H,2-3,5-6,8-11H2,1H3,(H,23,24)/b7-4-,14-12+/t16-,17-,18+/m0/s1
InChIKey
MYHXHCUNDDAEOZ-FOSBLDSVSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Transient receptor potential cation channel subfamily A member 1 Target Info Activator [529635]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 541431(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6279).
Ref 529635Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):12045-50.

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