Drug Information

Drug General Information
Drug ID
D07MBQ
Former ID
DIB011353
Drug Name
CNTO-736
Synonyms
GLP-1 mimetibody (type 2 diabetes), Centocor
Indication Non-insulin dependent diabetes [ICD10:E11.9] Investigative [543638]
Company
Centocor Ortho Biotech Inc
Target and Pathway
Target(s) Glucagon-like peptide 1 receptor Target Info Modulator [543638]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Reactome Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
G alpha (s) signalling events
Glucagon-type ligand receptors
WikiPathways GPCRs, Class B Secretin-like
Integration of energy metabolism
GPCR ligand binding
GPCR downstream signaling
References
Ref 543638(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 249).
Ref 543638(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 249).

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