Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07NJI
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| Former ID |
DAP001450
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| Drug Name |
Treximet
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| Synonyms |
Trexima; Naproxen mixture with sumatriptan; Naproxen sodium mixture with sumatriptan succinate; Sumatriptan mixture with naproxen;Sumatriptan succinate and naproxen sodium; Sumatriptan succinate mixture with naproxen sodium; Naproxen / sumatriptan
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| Drug Type |
Small molecular drug
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| Indication | Migraine [ICD9: 346; ICD10:G43] | Approved | [538578] | ||
| Company |
GSK
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| Structure |
|
Download2D MOL |
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| Formula |
C32H40N3NaO9S
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| Canonical SMILES |
CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)[O-].CNS(=O)(=O)CC1=C<br />C2=C(C=C1)NC=C2CCN(C)C.C(CC(=O)O)C(=O)O.[Na+]
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| InChI |
1S/C14H21N3O2S.C14H14O3.C4H6O4.Na/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3;1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;5-3(6)1-2-4(7)8;/h4-5,8-9,15-16H,6-7,10H2,1-3H3;3-9H,1-2H3,(H,15,16);1-2H2,(H,5,6)(H,7,8);/q;;;+1/p-1/t;9-;;/m.0../s1
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| InChIKey |
IGRAQVLKCQVBQA-DBQHITQZSA-M
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| CAS Number |
CAS 154189-24-9
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | 5-hydroxytryptamine 1A receptor | Target Info | Antagonist | [550963] | |
| References | |||||
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