Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D07OGZ
|
||||
Former ID |
DNCL001895
|
||||
Drug Name |
Darexaban maleate
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Acute coronary syndrome [ICD9: 444; ICD10:I74] | Discontinued in Phase 3 | [547958] | ||
Company |
Astellas Pharma
|
||||
Structure |
Download2D MOL |
||||
Formula |
C31H34N4O8
|
||||
Canonical SMILES |
CN1CCCN(CC1)C2=CC=C(C=C2)C(=O)NC3=C(C=CC=C3O)NC(=O)C4=C<br />C=C(C=C4)OC.C(=CC(=O)O)C(=O)O
|
||||
InChI |
1S/C27H30N4O4.C4H4O4/c1-30-15-4-16-31(18-17-30)21-11-7-19(8-12-21)27(34)29-25-23(5-3-6-24(25)32)28-26(33)20-9-13-22(35-2)14-10-20;5-3(6)1-2-4(7)8/h3,5-14,32H,4,15-18H2,1-2H3,(H,28,33)(H,29,34);1-2H,(H,5,6)(H,7,8)/b;2-1-
|
||||
InChIKey |
WHMPMUVISXATBH-BTJKTKAUSA-N
|
||||
PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Coagulation factor Xa | Target Info | Inhibitor | [531926] | |
KEGG Pathway | Complement and coagulation cascades | ||||
PANTHER Pathway | Blood coagulation | ||||
Pathway Interaction Database | Beta2 integrin cell surface interactions | ||||
PathWhiz Pathway | Coagulation | ||||
Reactome | Extrinsic Pathway of Fibrin Clot Formation | ||||
Intrinsic Pathway of Fibrin Clot Formation | |||||
Common Pathway of Fibrin Clot Formation | |||||
Gamma-carboxylation of protein precursors | |||||
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | |||||
Removal of aminoterminal propeptides from gamma-carboxylated proteins | |||||
References |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.