Drug General Information
Drug ID	D07PTH
Former ID	DIB012605
Drug Name	13-cis-retinoic acid, UCSD
Synonyms	CRA, UCSD; 13-cis-retinoic acid
Indication	Glioma [ICD9: 191; ICD10:C71]		Phase 3	[525348]
Company	University of California San Diego
Structure		Download 2D MOL 3D MOL
Canonical SMILES	C1(=C(CCCC1(C)C)C)/C=C/C(=C/C=C/C(=C\C(=O)O)/C)/C
Target and Pathway
Target(s)	Retinoic acid receptor	Target Info	Modulator	[525851], [551871]
References
Ref 525348	Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML. Cell. 1991 Aug 23;66(4):663-74.
Ref 525851	13-cis retinoic acid exerts its specific activity on human sebocytes through selective intracellular isomerization to all-trans retinoic acid and binding to retinoid acid receptors. J Invest Dermatol. 2000 Aug;115(2):321-7.
Ref 551871	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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