Drug Information
Drug General Information | |||||
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Drug ID |
D07RMP
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Former ID |
DNC000825
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Drug Name |
J-113397
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [539046] | ||
Structure |
Download2D MOL |
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Formula |
C24H37N3O2
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InChI |
InChI=1S/C24H37N3O2/c1-2-26-22-12-8-9-13-23(22)27(24(26)29)21-14-15-25(17-20(21)18-28)16-19-10-6-4-3-5-7-11-19/h8-9,12-13,19-21,28H,2-7,10-11,14-18H2,1H3/t20-,21+/m0/s1
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InChIKey |
MBGVUMXBUGIIBQ-LEWJYISDSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Nociceptin receptor | Target Info | Antagonist | [535360], [535745], [536893] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
References | |||||
Ref 535360 | Nociceptin receptor antagonists display antidepressant-like properties in the mouse forced swimming test. Naunyn Schmiedebergs Arch Pharmacol. 2002 Feb;365(2):164-7. Epub 2001 Dec 20. | ||||
Ref 535745 | The nociceptin receptor as a potential target in drug design. Drug News Perspect. 2001 Aug;14(6):335-45. | ||||
Ref 536893 | Nocistatin and nociceptin given centrally induce opioid-mediated gastric mucosal protection. Peptides. 2008 Dec;29(12):2257-65. Epub 2008 Sep 26. |
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