TTD | Drug: D07SCN

Drug General Information
Drug ID	D07SCN
Former ID	DIB004168
Drug Name	KC-11458
Indication	Gastric motility disorder [ICD10:K22.4]		Discontinued in Phase 2	[546439]
Company	Solvay SA
Target and Pathway
Target(s)	Motilin receptor	Target Info	Modulator	[527150]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 546439	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008138)
Ref 527150	Effect of the motilin agonist KC 11458 on gastric emptying in diabetic gastroparesis. Aliment Pharmacol Ther. 2004 Aug 1;20(3):333-8.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information