Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07UFO
|
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| Former ID |
DIB018530
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| Drug Name |
20-HETE
|
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| Synonyms |
20-hydroxyeicosatetraenoic acid
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C20H32O3
|
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| InChI |
InChI=1S/C20H32O3/c21-19-17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-18-20(22)23/h1,3-4,6-7,9-10,12,21H,2,5,8,11,13-19H2,(H,22,23)/b3-1-,6-4-,9-7-,12-10-
|
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| InChIKey |
NNDIXBJHNLFJJP-DTLRTWKJSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
4266115, 11038791, 14718392, 14801405, 17395746, 24895546, 39316571, 49964844, 53790793, 57358870, 74666386, 113859256, 126524524, 126525564, 135079354, 137017133, 141469038, 162228697, 164796070, 178100926, 179293501, 184586025, 186022450, 210275257, 210280898, 226819771, 241138961, 250132926, 252371236, 252464960
|
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| Target and Pathway | |||||
| Target(s) | Short transient receptor potential channel 6 | Target Info | Activator | [2] | |
| PANTHER Pathway | Alzheimer disease-presenilin pathway | ||||
| Pathway Interaction Database | Endothelins | ||||
| Nephrin/Neph1 signaling in the kidney podocyte | |||||
| EPO signaling pathway | |||||
| PAR1-mediated thrombin signaling events | |||||
| Reactome | Effects of PIP2 hydrolysis | ||||
| TRP channels | |||||
| Role of second messengers in netrin-1 signaling | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| Platelet homeostasis | |||||
| Netrin-1 signaling | |||||
| GPCR downstream signaling | |||||
| Effects of PIP2 hydrolysis | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4103). | ||||
| REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 491). | ||||
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