TTD | Drug: D08BSG

Drug General Information
Drug ID	D08BSG
Former ID	DNC003690
Drug Name	IODOPROXYFAN
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538768]
Structure		Download 2D MOL 3D MOL
Formula	C13H15IN2O
InChI	InChI=1S/C13H15IN2O/c14-12-5-3-11(4-6-12)9-17-7-1-2-13-8-15-10-16-13/h3-6,8,10H,1-2,7,9H2,(H,15,16)
InChIKey	DCQNAFOCXVCDLB-UHFFFAOYSA-N
PubChem Compound ID	132937
PubChem Substance ID	7979633, 14827257, 29310960, 47731205, 48329024, 49846730, 50537305, 53999591, 57344316, 85218026, 103183957, 103947354, 104378585, 126437528, 127715461, 134340895, 135088535, 135650406, 179293864, 229137555
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Inhibitor	[526023]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
Reactome	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 538768	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1253).
Ref 526023	Bioorg Med Chem Lett. 2001 Apr 9;11(7):951-4.Different antagonist binding properties of human and rat histamine H3 receptors.

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Drug Information