Drug General Information
Drug ID
D08DTD
Former ID
DIB009257
Drug Name
Biostrophin
Synonyms
Duchenne muscular dystrophy therapy, Asklepios; Adeno-associated virus gene therapy (dystrophin), AskBio; Adeno-associated virus gene therapy (dystrophin), Asklepios
Indication Duchenne muscular dystrophy [ICD10:G71.0] Phase 1 [548212]
Company
Asklepios biopharmaceuticals
Target and Pathway
Target(s) Dystrophin Target Info Modulator [525393]
KEGG Pathway Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Viral myocarditis
NetPath Pathway IL4 Signaling Pathway
IL5 Signaling Pathway
Reactome Non-integrin membrane-ECM interactions
Striated Muscle Contraction
WikiPathways Striated Muscle Contraction
Ectoderm Differentiation
Extracellular matrix organization
Arrhythmogenic Right Ventricular Cardiomyopathy
Muscle contraction
References
Ref 548212Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023141)
Ref 525393Therapy for Duchenne muscular dystrophy: renewed optimism from genetic approaches. Nat Rev Genet. 2013 Jun;14(6):373-8. doi: 10.1038/nrg3460. Epub 2013 Apr 23.

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