Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08DTT
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| Former ID |
DIB000559
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| Drug Name |
Androgen receptor modulators
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| Synonyms |
Androgen receptor modulators (osteoporosis); Androgen agonists (osteoporosis), Merck & Co; Androgen receptor modulators (osteoporosis), Merck & Co; SARMs (osteoporosis), Merck & Co
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| Indication | Osteoporosis [ICD9: 733.0, V07.4; ICD10:M80-M81, Z79.890] | Investigative | [530821] | ||
| Company |
Merck & Co Inc
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
[nH]1c(nc2c1cccn2)C[C@@H]1[C@]2(CC[C@@H]3[C@]4(C=CC(=O)<br />N(C4CC[C@H]3[C@@H]2CC1)C)C)C
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| Target and Pathway | |||||
| Target(s) | Androgen receptor | Target Info | Agonist | [1572605] | |
| Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
| Coregulation of Androgen receptor activity | |||||
| Regulation of Androgen receptor activity | |||||
| Nongenotropic Androgen signaling | |||||
| Regulation of nuclear beta catenin signaling and target gene transcription | |||||
| FOXA1 transcription factor network | |||||
| Notch-mediated HES/HEY network | |||||
| References | |||||
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