Drug Information

Drug General Information
Drug ID
D08EEO
Former ID
DIB001704
Drug Name
Demobesin
Synonyms
Bombesin antagonist (prostate/breast/NSCL), Biomedica lifesciences; 99mTc-Demobesin-6
Indication Breast cancer [ICD9: 174, 175; ICD10:C50] Phase 1 [522810]
Company
Biomedica Life Sciences SA
Target and Pathway
Target(s) Bombesin receptor Target Info Antagonist [543802]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
References
Ref 522810ClinicalTrials.gov (NCT00989105) Technetium Tc 99m Demobesin-4 for Imaging Procedures in Patients With Prostate Cancer. U.S. National Institutes of Health.
Ref 543802(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 38).

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