Drug Information

Drug General Information
Drug ID
D08EZR
Former ID
DNC002831
Drug Name
5-Iodouracil
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL
Formula
C4H3IN2O2
Canonical SMILES
C1=C(C(=O)NC(=O)N1)I
InChI
1S/C4H3IN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
InChIKey
KSNXJLQDQOIRIP-UHFFFAOYSA-N
PubChem Compound ID
69672
PubChem Substance ID
106724, 595839, 630496, 821031, 821038, 1582642, 3139702, 5830660, 5903128, 7868912, 7888491, 8193148, 15044327, 24888454, 43126129, 46507512, 46529921, 49834729, 50059616, 57317492, 77914273, 81065691, 85087021, 85245873, 87571594, 87793161, 88289968, 88802969, 92717671, 99583041, 103145466, 103158233, 103341945, 104016560, 104345590, 117511586, 117664335, 117773462, 117816393, 118068104, 124437990, 124550805, 125356313, 126581505, 126628772, 126653756, 126689959, 126738400, 127287426, 127287427
Target and Pathway
Target(s) Dihydropyrimidine dehydrogenase [NADP+] Target Info Inhibitor [551393]
BioCyc Pathway Pyrimidine ribonucleosides degradation
Thymine degradation
Uracil degradation
KEGG Pathway Pyrimidine metabolism
beta-Alanine metabolism
Pantothenate and CoA biosynthesis
Drug metabolism - other enzymes
Metabolic pathways
PANTHER Pathway Pyrimidine Metabolism
PathWhiz Pathway Beta-Alanine Metabolism
Pyrimidine Metabolism
WikiPathways Metabolism of nucleotides
Fluoropyrimidine Activity
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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