Drug Information

Drug General Information
Drug ID
D08FMR
Former ID
DIB003740
Drug Name
ARC-1905
Synonyms
Aptamer C5 inhibitors (age-related macular degeneration), Archemix/Ophthotech
Drug Type
Aptamer
Indication Macular degeneration [ICD9: 362.5; ICD10:H35.3] Phase 1 [522747]
Company
Archemix Corp
Target and Pathway
Target(s) Complement C5 Target Info [522747]
KEGG Pathway Complement and coagulation cascades
Prion diseases
Pertussis
Staphylococcus aureus infection
Herpes simplex infection
Systemic lupus erythematosus
Reactome Activation of C3 and C5
Peptide ligand-binding receptors
G alpha (i) signalling events
Regulation of Complement cascade
WikiPathways Complement Activation, Classical Pathway
Human Complement System
Spinal Cord Injury
Allograft Rejection
GPCR ligand binding
GPCR downstream signaling
Complement cascade
References
Ref 522747ClinicalTrials.gov (NCT00950638) A Study of ARC1905 (Anti-C5 Aptamer) in Subjects With Dry Age-related Macular Degeneration. U.S. National Institutes of Health.
Ref 522747ClinicalTrials.gov (NCT00950638) A Study of ARC1905 (Anti-C5 Aptamer) in Subjects With Dry Age-related Macular Degeneration. U.S. National Institutes of Health.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.