Drug Information

Drug General Information
Drug ID
D08FNJ
Former ID
DIB006001
Drug Name
RO-14
Synonyms
Very low molecular weight heparin (venous thromboembolism), Rovi
Indication Phlebothrombosis [ICD10:I80-I82] Phase 1 [522244]
Company
Laboratorios Farmaceuticos Rovi SA
Target and Pathway
Target(s) Antithrombin-III Target Info Modulator [532712]
KEGG Pathway Complement and coagulation cascades
PANTHER Pathway Blood coagulation
Pathway Interaction Database Glypican 1 network
Reactome Intrinsic Pathway of Fibrin Clot Formation
Common Pathway of Fibrin Clot Formation
WikiPathways Complement and Coagulation Cascades
Formation of Fibrin Clot (Clotting Cascade)
References
Ref 522244ClinicalTrials.gov (NCT00629733) Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of a New Ultra Low Molecular Weight Heparin (RO-14) Administered Subcutaneously Increasing Single-doses to Healthy Male Volunteers. U.S. National Institutes of Health.
Ref 532712Pharmacological effects and clinical applications of ultra low molecular weight heparins. Drug Discov Ther. 2014 Feb;8(1):1-10.

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