Drug General Information
Drug ID	D08FTP
Former ID	DIB006115
Drug Name	99mTc-MIP-1404
Indication	Prostate cancer [ICD9: 185; ICD10:C61]		Phase 2	[524028]
Company	Molecular Insight Pharmaceuticals Inc
Structure		Download 2D MOL
Target and Pathway
Target(s)	Glutamate carboxypeptidase II	Target Info	Modulator	[532384]
KEGG Pathway	Alanine, aspartate and glutamate metabolism
	Metabolic pathways
	Vitamin digestion and absorption
NetPath Pathway	TCR Signaling Pathway
	TNFalpha Signaling Pathway
Reactome	Amino acid synthesis and interconversion (transamination)
WikiPathways	One Carbon Metabolism
References
Ref 524028	ClinicalTrials.gov (NCT01667536) A Phase 2 Diagnostic Imaging Study With 99mTc-MIP-1404 in Men With High-Risk Prostate Cancer Scheduled for Radical Prostatectomy (RP) and Extended Pelvic Lymph Node Dissection (EPLND) Compared to Histopathology. U.S. National Institutes of Health.
Ref 532384	99mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen for molecular imaging of prostate cancer. J Nucl Med. 2013 Aug;54(8):1369-76.

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