Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08HGK
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| Former ID |
DNC011494
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| Drug Name |
N-Benzyl-2-(1H-indol-3-yl)-2-oxo-acetamide
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| Synonyms |
N-benzyl-2-(1H-indol-3-yl)-2-oxoacetamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [528709] | ||
| Structure |
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Download2D MOL |
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| Formula |
C17H14N2O2
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| Canonical SMILES |
C1=CC=C(C=C1)CNC(=O)C(=O)C2=CNC3=CC=CC=C32
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| InChI |
1S/C17H14N2O2/c20-16(14-11-18-15-9-5-4-8-13(14)15)17(21)19-10-12-6-2-1-3-7-12/h1-9,11,18H,10H2,(H,19,21)
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| InChIKey |
HWOWPGLTTSFLOQ-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Gamma-aminobutyric acid receptor subunit alpha-1 | Target Info | Inhibitor | [528709] | |
| Gamma-aminobutyric acid receptor subunit beta-2 | Target Info | Inhibitor | [528709] | ||
| Gamma-aminobutyric acid receptor subunit gamma-2 | Target Info | Inhibitor | [528709] | ||
| Gamma-aminobutyric acid receptor | Target Info | Inhibitor | [534710] | ||
| References | |||||
| Ref 528709 | J Med Chem. 2007 Apr 5;50(7):1627-34. Epub 2007 Mar 3.Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1/L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands. | ||||
| Ref 534710 | J Med Chem. 1998 Sep 24;41(20):3821-30.N'-Phenylindol-3-ylglyoxylohydrazide derivatives: synthesis, structure-activity relationships, molecular modeling studies, and pharmacological action on brain benzodiazepine receptors. | ||||
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