Drug General Information
Drug ID	D08HSQ
Former ID	DNC008899
Drug Name	C[Glu22-Lys26][Gly8]GLP-1(7-37)-NH2
Indication	Discovery agent		Investigative	[529424]
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Glucagon-like peptide 1 receptor	Target Info	Inhibitor	[529424]
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Insulin secretion
Reactome	Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
	G alpha (s) signalling events
	Glucagon-type ligand receptors
WikiPathways	GPCRs, Class B Secretin-like
	Integration of energy metabolism
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 529424	J Med Chem. 2008 May 8;51(9):2758-65. Epub 2008 Apr 15.Design and synthesis of conformationally constrained glucagon-like peptide-1 derivatives with increased plasma stability and prolonged in vivo activity.
Ref 529424	J Med Chem. 2008 May 8;51(9):2758-65. Epub 2008 Apr 15.Design and synthesis of conformationally constrained glucagon-like peptide-1 derivatives with increased plasma stability and prolonged in vivo activity.

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