Drug General Information
Drug ID	D08JEK
Drug Name	Org-30850
Synonyms	136208-71-4; Org-300850; Org-30850
Drug Type	Small molecular drug
Indication	Unspecified		Investigative	[1560193]
Structure		Download 2D MOL
Formula	C69H91Cl2N15O13S
PubChem Compound ID	44384543
Target and Pathway
Target(s)	Gonadotropin-releasing hormone receptor	Target Info	Modulator
KEGG Pathway	Neuroactive ligand-receptor interaction
	GnRH signaling pathway
NetPath Pathway	IL1 Signaling Pathway
	IL2 Signaling Pathway
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome	Hormone ligand-binding receptors
	G alpha (q) signalling events
WikiPathways	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 1560193	In vivo effects of a potent GnRH antagonist ORG 30850: physiologic evidence that down-regulation of GnRH receptors does not occur.

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