Drug Information

Drug General Information
Drug ID
D08KBY
Former ID
DIB018429
Drug Name
[3H]UBP310
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540688]
Formula
C14H15N3O6S
InChI
InChI=1S/C14H15N3O6S/c1-7-4-16(6-9(15)12(19)20)14(23)17(11(7)18)5-8-2-3-24-10(8)13(21)22/h2-4,9H,5-6,15H2,1H3,(H,19,20)(H,21,22)/t9-/m0/s1
InChIKey
ZTAZUCRXCRXNSU-VIFPVBQESA-N
PubChem Compound ID
6420160
Target and Pathway
Target(s) GluK3 Target Info Antagonist [531158]
Glutamate receptor, ionotropic kainate 1 Target Info Antagonist [531158]
KEGG Pathway Neuroactive ligand-receptor interaction
Glutamatergic synapse
PANTHER Pathway Huntington disease
Ionotropic glutamate receptor pathway
Metabotropic glutamate receptor group III pathway
Metabotropic glutamate receptor group I pathway
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 540688(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4092).
Ref 531158Mapping the ligand binding sites of kainate receptors: molecular determinants of subunit-selective binding of the antagonist [3H]UBP310. Mol Pharmacol. 2010 Dec;78(6):1036-45.

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