Drug Information

Drug General Information
Drug ID
D08LVH
Former ID
DIB020321
Drug Name
medica 16
Synonyms
medic-16
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538636]
Structure
Download
2D MOL
Formula
C20H38O4
InChI
InChI=1S/C20H38O4/c1-19(2,15-17(21)22)13-11-9-7-5-6-8-10-12-14-20(3,4)16-18(23)24/h5-16H2,1-4H3,(H,21,22)(H,23,24)
InChIKey
HYSMCRNFENOHJH-UHFFFAOYSA-N
PubChem Compound ID
121871
PubChem Substance ID
10239841, 14802489, 24724539, 29217592, 29302369, 50070425, 50071065, 78694693, 103125133, 103257527, 103929673, 104414472, 117547488, 123220345, 125334875, 128132412, 135077518, 135650576, 137329263, 138205701, 162248371, 224885153, 226546166, 241150839, 241377087, 252158216, 252457657, 252468081
Target and Pathway
Target(s) GPR40 Target Info Agonist [526529]
KEGG Pathway Insulin secretion
Reactome G alpha (q) signalling events
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
WikiPathways GPCRs, Class A Rhodopsin-like
Incretin Synthesis, Secretion, and Inactivation
Gastrin-CREB signalling pathway via PKC and MAPK
Integration of energy metabolism
GPCR ligand binding
GPCR downstream signaling
References
Ref 538636(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1053).
Ref 526529A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs. Biochem Biophys Res Commun. 2003 Feb 7;301(2):406-10.

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