Drug Information

Drug General Information
Drug ID
D08MVV
Former ID
DIB006259
Drug Name
PRX-111
Synonyms
FSH variants (female infertility), Protalix Biotherapeutics/ Compugen; Follicle stimulating hormone variants (female infertility), Protalix Biotherapeutics/ Compugen
Indication Female infertility [ICD9: 628; ICD10:N97.0] Investigative [548736]
Company
Protalix BioTherapeutics Inc
Target and Pathway
Target(s) Follicle stimulating hormone receptor Target Info Modulator [534648]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Ovarian steroidogenesis
PathWhiz Pathway Vasopressin Regulation of Water Homeostasis
Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone
Reactome Hormone ligand-binding receptors
G alpha (s) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Ovarian Infertility Genes
Peptide GPCRs
FSH signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 548736Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028182)
Ref 534648A naturally occurring basically charged human follicle-stimulating hormone (FSH) variant inhibits FSH-induced androgen aromatization and tissue-type plasminogen activator enzyme activity in vitro. Neuroendocrinology. 1998 Mar;67(3):153-63.

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