Drug Information

Drug General Information
Drug ID
D08NXW
Former ID
DIB010220
Drug Name
GLP-1
Synonyms
Oral GLP (diabetes, eligen), Emisphere; GLP-1 (oral tablet, Eligen, diabetes); Glucagon-like peptides (oral, eligen), Emisphere; GLP-1 (oral tablet, Eligen, diabetes), Emisphere
Indication Diabetes [ICD9: 253.5, 588.1; ICD10:E23.2, N25.1] Phase 3 [549904]
Company
Emisphere Technologies Inc
Structure
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2D MOL

3D MOL
Formula
C149H226N40O45
PubChem Compound ID
16135499
Target and Pathway
Target(s) Glucagon-like peptide 1 receptor Target Info Modulator [543638]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Reactome Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
G alpha (s) signalling events
Glucagon-type ligand receptors
WikiPathways GPCRs, Class B Secretin-like
Integration of energy metabolism
GPCR ligand binding
GPCR downstream signaling
References
Ref 549904Clinical pipeline report, company report or official report of Emisphere Technologies Inc.
Ref 543638(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 249).

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