TTD | Drug: D08OYH

Drug General Information
Drug ID	D08OYH
Former ID	DNC014335
Drug Name	O5-Acetyl-O7-nitrooxyethyl chrysin
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530856]
Structure		Download 2D MOL 3D MOL
Formula	C19H15NO8
Canonical SMILES	CC(=O)OC1=C2C(=CC(=C1)OCCO[N+](=O)[O-])OC(=CC2=O)C3=CC=<br />CC=C3
InChI	1S/C19H15NO8/c1-12(21)27-17-9-14(25-7-8-26-20(23)24)10-18-19(17)15(22)11-16(28-18)13-5-3-2-4-6-13/h2-6,9-11H,7-8H2,1H3
InChIKey	VQDIDXYXZUUTEY-UHFFFAOYSA-N
PubChem Compound ID	46887248
Target and Pathway
Target(s)	Aldose reductase	Target Info	Inhibitor	[530856]
BioCyc Pathway	Methylglyoxal degradation III
BioCyc Pathway	Acetone degradation I (to methylglyoxal)
KEGG Pathway	Pentose and glucuronate interconversions
	Fructose and mannose metabolism
	Galactose metabolism
	Glycerolipid metabolism
	Metabolic pathways
NetPath Pathway	IL1 Signaling Pathway
NetPath Pathway	TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway	Fructose and Mannose Degradation
	Pyruvate Metabolism
	Pterine Biosynthesis
	Glycerolipid Metabolism
	Galactose Metabolism
WikiPathways	Metapathway biotransformation
	Polyol Pathway
	Metabolism of steroid hormones and vitamin D
References
Ref 530856	Bioorg Med Chem. 2010 May 1;18(9):3020-5. Epub 2010 Mar 27.Synthesis, characterization and vasculoprotective effects of nitric oxide-donating derivatives of chrysin.
Ref 530856	Bioorg Med Chem. 2010 May 1;18(9):3020-5. Epub 2010 Mar 27.Synthesis, characterization and vasculoprotective effects of nitric oxide-donating derivatives of chrysin.

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Drug Information