Drug Information

Drug General Information
Drug ID
D08SJZ
Former ID
DAP001022
Drug Name
Ibandronate
Synonyms
BFQ; Bondronat; Boniva; Bonviva; Acid ibandronico; IBANDRONATE SODIUM; Ibandronic Acid; BM 210955;Bisphosphonate 2; R484; RPR 102289A; BM 21.0955; BM-210955; Bondronat (TN); Boniva (TN); Bonviva (TN); Ibandronic acid (INN); Ibandronic acid [INN:BAN]; RPR-102289A; BM-21.0955; Ibandronic acid, sodium salt, monohydrate; Roche brand of ibandronic acid, sodium salt, monohydrate; [1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonopropyl]phosphonic acid; [1-HYDROXY-3-(METHYL-PENTYL-AMINO)-1-PHOSPHONO-PROPYL]-PHOSPHONIC ACID; (1-Hydroxy-3-(methylpentylamino)propylidene)diphosphonic acid; (1-hydroxy-3-(methylpentylamino)propylidene)bisphosphonate; 1-hydroxy-3-(methylpentylamino)propylidenebisphosphonate
Drug Type
Small molecular drug
Indication Osteoporosis in post-menopausal women [ICD9: 733; ICD10:M80-M81] Approved [537046], [540061]
Therapeutic Class
Bone Density Conservation Agents
Company
Roche; GlaxoSmithKline
Structure
Download
2D MOL

3D MOL
Formula
C9H23NO7P2
InChI
InChI=1S/C9H23NO7P2/c1-3-4-5-7-10(2)8-6-9(11,18(12,13)14)19(15,16)17/h11H,3-8H2,1-2H3,(H2,12,13,14)(H2,15,16,17)
InChIKey
MPBVHIBUJCELCL-UHFFFAOYSA-N
CAS Number
CAS 114084-78-5
PubChem Compound ID
60852
PubChem Substance ID
7843823, 7978906, 8187097, 10318381, 14899229, 17137086, 43118190, 46504766, 46508134, 46513034, 50067809, 50070897, 50352086, 57309756, 57314150, 85175518, 92309009, 92719342, 96024748, 103265985, 104321814, 117626546, 125338459, 126584244, 126628258, 126653235, 126670896, 128627634, 134338290, 135030117, 135603369, 135649664, 136990668, 137008722, 142216113, 151995142, 160964054, 162176651, 163122790, 163417770, 164787819, 172439442, 172854478, 175267950, 176484248, 177748834, 179149628, 196105630, 204371129, 210279677
SuperDrug ATC ID
M05BA06
Target and Pathway
Target(s) Farnesyl pyrophosphate synthase Target Info Modulator [556264]
BioCyc Pathway Superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate)
Superpathway of cholesterol biosynthesis
Trans, trans-farnesyl diphosphate biosynthesis
KEGG Pathway Terpenoid backbone biosynthesis
Metabolic pathways
Biosynthesis of antibiotics
Influenza A
HTLV-I infection
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Cholesterol biosynthesis
References
Ref 537046Efficacy of bisphosphonates in reducing fracture risk in postmenopausal osteoporosis. Am J Med. 2009 Feb;122(2 Suppl):S14-21.
Ref 540061(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3059).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.