Drug Information

Drug General Information
Drug ID
D08SOE
Former ID
DIB019272
Drug Name
compound 17
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528543], [538802]
Structure
Download
2D MOL
Formula
C28H24ClN3OS
InChI
InChI=1S/C28H24ClN3OS/c29-23-9-6-20(7-10-23)26-16-25-27(34-26)28(33)32(18-30-25)24-11-8-21-14-19(4-5-22(21)15-24)17-31-12-2-1-3-13-31/h4-11,14-16,18H,1-3,12-13,17H2
InChIKey
FJPBPFUKHDZYIJ-UHFFFAOYSA-N
PubChem Compound ID
11994411
PubChem Substance ID
17493529, 26546832, 37442790, 75821141, 103501812, 104079922, 135650121, 139290258, 231709861, 243721811
Target and Pathway
Target(s) Melanin-concentrating hormone receptor 1 Target Info Antagonist [528543]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 5285436-(4-chlorophenyl)-3-substituted-thieno[3,2-d]pyrimidin-4(3H)-one-based melanin-concentrating hormone receptor 1 antagonist. J Med Chem. 2006 Nov 30;49(24):7108-18.
Ref 538802(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1306).
Ref 5285436-(4-chlorophenyl)-3-substituted-thieno[3,2-d]pyrimidin-4(3H)-one-based melanin-concentrating hormone receptor 1 antagonist. J Med Chem. 2006 Nov 30;49(24):7108-18.

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