Drug General Information
Drug ID
D08URY
Former ID
DIB018823
Drug Name
alpha-methylphenylalanine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [468155]
Structure
Download
2D MOL
Formula
C10H13NO2
InChI
InChI=1S/C10H13NO2/c1-10(11,9(12)13)7-8-5-3-2-4-6-8/h2-6H,7,11H2,1H3,(H,12,13)
InChIKey
HYOWVAAEQCNGLE-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Phenylalanine hydroxylase Target Info Inhibitor [534546]
BioCyc Pathway Phenylalanine degradation/tyrosine biosynthesis
KEGG Pathway Phenylalanine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Metabolic pathways
Biosynthesis of amino acids
PathWhiz Pathway Phenylalanine and Tyrosine Metabolism
WikiPathways SIDS Susceptibility Pathways
Biogenic Amine Synthesis
Metabolism of amino acids and derivatives
Abnormal metabolism in phenylketonuria
References
Ref 468155(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5093).
Ref 534546Alpha-methylphenylalanine, a new inducer of chronic hyperphenylalaninemia in sucling rats. Science. 1976 Jun 4;192(4243):1007-8.

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