| Drug General Information |
| Drug ID |
D08XCD
|
| Former ID |
DNC003251
|
| Drug Name |
2-(cyclohexylamino)benzoic acid
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C13H17NO2
|
| Canonical SMILES |
C1CCC(CC1)NC2=CC=CC=C2C(=O)O
|
| InChI |
1S/C13H17NO2/c15-13(16)11-8-4-5-9-12(11)14-10-6-2-1-3-7-10/h4-5,8-10,14H,1-3,6-7H2,(H,15,16)
|
| InChIKey |
JSXMFCCPQQJLCR-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
47613059, 54927073, 56435703, 93307419, 99443509, 125686171, 128322956, 145625082, 160968123, 164120617, 184596774, 223589217, 229305345, 249746101
|
| Target and Pathway |
| Target(s) |
Serine/threonine-protein kinase Chk1 |
Target Info |
Inhibitor |
[1]
|
|---|
|
KEGG Pathway
|
Cell cycle
|
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p53 signaling pathway
|
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HTLV-I infection
|
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Viral carcinogenesis
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Pathway Interaction Database
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Fanconi anemia pathway
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p73 transcription factor network
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ATR signaling pathway
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Circadian rhythm pathway
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p53 pathway
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Reactome
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Activation of ATR in response to replication stress
|
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Processing of DNA double-strand break ends
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Presynaptic phase of homologous DNA pairing and strand exchange
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G2/M DNA damage checkpoint
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Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
|
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Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
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WikiPathways
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DNA Damage Response
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Signaling by SCF-KIT
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ATM Signaling Pathway
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Retinoblastoma (RB) in Cancer
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Integrated Pancreatic Cancer Pathway
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Prostate Cancer
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Integrated Breast Cancer Pathway
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Integrated Cancer pathway
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Cell Cycle
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Cell Cycle Checkpoints
|
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miRNA Regulation of DNA Damage Response
|
| References |
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
|---|
