Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08XKL
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| Former ID |
DIB013558
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| Drug Name |
SPI-014
|
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| Synonyms |
SPI-1802; SPI-1810; Amyloid beta peptide 1-42 deposition inhibitor (AD), Satori; Gamma-secretase modulators (Alzheimers disease), Satori Pharmaceuticals
|
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| Indication | Alzheimer disease [ICD9: 331; ICD10:G30] | Phase 1 | [523843] | ||
| Company |
Satori Pharmaceuticals Inc
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| Structure |
|
Download2D MOL |
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| Target and Pathway | |||||
| Target(s) | Gamma-secretase | Target Info | Modulator | [532197] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| NOTCH2 Activation and Transmission of Signal to the Nucleus | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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