Drug Information

Drug General Information
Drug ID
D09APA
Former ID
DIB004939
Drug Name
Plasma derived factor VIII PEGylated liposomal
Synonyms
LongAte; NecLip-pdFVIII; Plasma derived factor VIII (PEGylated liposomal (NecLip), hemophilia A), Recoly
Indication Factor VIII deficiency [ICD10:D66] Phase 3 [544080]
Company
Recoly NV
Target and Pathway
Target(s) Coagulation Factor VIIIa Target Info Modulator [543658]
KEGG Pathway Complement and coagulation cascades
PANTHER Pathway Blood coagulation
PathWhiz Pathway Coagulation
Reactome Platelet degranulation
Intrinsic Pathway of Fibrin Clot Formation
Common Pathway of Fibrin Clot Formation
COPII (Coat Protein 2) Mediated Vesicle Transport
Cargo concentration in the ER
WikiPathways Complement and Coagulation Cascades
Blood Clotting Cascade
Formation of Fibrin Clot (Clotting Cascade)
References
Ref 544080Recombinant factor VIII in the management of hemophilia A: current use and future promise. Ther Clin Risk Manag. 2009; 5: 391-402.
Ref 543658(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2607).

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