Drug General Information
Drug ID
D09BVL
Former ID
DIB002312
Drug Name
NS-1619
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Terminated [467609], [545014]
Company
NeuroSearch A/S
Structure
Download
2D MOL

3D MOL

Formula
C15H8F6N2O2
InChI
InChI=1S/C15H8F6N2O2/c16-14(17,18)7-1-3-10-9(5-7)22-13(25)23(10)11-6-8(15(19,20)21)2-4-12(11)24/h1-6,24H,(H,22,25)
InChIKey
YLFMCMWKHSDUCT-UHFFFAOYSA-N
CAS Number
CAS 153587-01-0
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Maxi K potassium channel Target Info Modulator
KEGG Pathway cGMP-PKG signaling pathway
Vascular smooth muscle contraction
Insulin secretion
Salivary secretion
Pancreatic secretion
Reactome cGMP effects
WikiPathways Potassium Channels
Platelet homeostasis
References
Ref 467609(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4272).
Ref 545014Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001878)

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.